• Users Online: 66
  • Print this page
  • Email this page
Year : 2022  |  Volume : 8  |  Issue : 1  |  Page : 16-19

Positivity of typhidot test in COVID cases: An observational cohort study from the second wave of the pandemic

1 Department of Respiratory Medicine, Santosh Medical College, Lucknow, Uttar Pradesh, India
2 Command Military Dental Centre, Central Command, Lucknow, Uttar Pradesh, India
3 Department of Respiratory Medicine, Santosh Deemed to be University, Ghaziabad, Uttar Pradesh, India

Correspondence Address:
Prachi Saxena
Department of Respiratory Medicine, Santosh Deemed to be University, Ghaziabad, Uttar Pradesh
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sujhs.sujhs_23_22

Rights and Permissions

Introduction: Typhidot has been known to cross-react with a variety of viral illnesses. There has been some communication throwing light on the possible false-positive results in COVID cases, but overall there is a dearth of studies directly investigating the association. This is a small-sized observational cohort study to detect and analyze the association between these two conditions. Materials and Methods: During a period of 1 month, starting from April 1, 2021, to April 30, 2021, all patients admitted with a Reverse Transcriptase- Polymerase Chain Reaction (RT-PCR)- positive report for SARS-CoV-2 to a nursing home in Ghaziabad were prescribed typhidot immunoglobulin M (IgM) test. Other parameters such as the radiological computed tomography score, hemoglobin levels, total leukocyte counts, serum glutamic-oxaloacetic transaminase, serum glutamic pyruvic transaminase enzyme levels, and the cycle threshold values of the RT-PCR test were recorded. The data thus collected were entered into a structured electronic data collection system and analyzed. Results: Thirty-seven percent of patients who were admitted with a diagnosis of RT-PCR-positive mild-to-moderate COVID pneumonia were also positive for typhoid IgM antibody. The distribution of this positive typhidot test was equal among both genders and was not found to be significantly associated with any of the other test variables. Conclusion: Our study reveals the anamnestic response of typhoid IgM antibodies against SARS-CoV-2. A positive typhidot test should not mislead or delay the diagnosis of any other viral respiratory illness.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded58    
    Comments [Add]    

Recommend this journal